Givosiran Market

Givosiran Market Size, Share & Industry Analysis, By Source (Solid-Phase Oligonucleotide Synthesis, Liquid-Phase Oligonucleotide Synthesis, Enzymatic Synthesis, Others), By Application (Acute Hepatic Porphyria Treatment, Research & Development, Off-Label Investigations, Combination Therapy Development), By End-User Industry (Pharmaceutical Companies, Hospitals & Clinics, Contract Manufacturing Organizations (CMOs), Research Institutes), and Forecast, 2025–2035

The Givosiran market is projected to grow at a considerable rate between 2025 and 2035, at a CAGR of 6.1%. This growth is primarily driven by the increasing incidence of rare diseases such as Acute Hepatic Porphyria (AHP), which Givosiran effectively treats. Additionally, growing awareness about personalized medicine, improved healthcare infrastructure, and the rise in research activities for new therapeutic indications contribute to the market’s expansion.

Regionally, North America is expected to maintain dominance due to its advanced healthcare systems, high prevalence of AHP, and a well-established market for orphan drugs. Europe also holds a significant share, supported by strong regulatory frameworks and the availability of patient support programs. However, the Asia-Pacific region is anticipated to see the fastest growth, driven by increasing healthcare access, growing patient populations, and local manufacturing initiatives in countries like China and India.

The market report benefits from an increase in funding for rare disease treatments, ongoing advancements in clinical research, and a broader adoption of gene-targeted therapies. Nevertheless, challenges such as pricing pressures, long approval processes, and the complexity of treatment regimens may impact growth in certain regions. However, increasing investments in gene therapy and biotechnology are likely to drive market expansion in the coming years.

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Report Scope & Segmentation

  1. Introduction
  • Overview of Givosiran
  • Key Applications & Industry Use Cases
  • Market Scope & Study Objectives
  1. Market Overview
  • Global Market Size & Growth Trends (Historical & Forecast)
  • Market Value & Revenue Analysis
  • Demand-Supply Dynamics
  1. Segmental Outlook
  • By Source
    • Solid-Phase Oligonucleotide Synthesis
    • Liquid-Phase Oligonucleotide Synthesis
    • Enzymatic Synthesis
    • Others
  • By Application
    • Acute Hepatic Porphyria Treatment
    • Research & Development
    • Off-Label Investigations
    • Combination Therapy Development
  • Key End-Use Industry
    • Pharmaceutical Companies
    • Hospitals & Clinics
    • Contract Manufacturing Organizations (CMOs)
    • Research Institutes

 

  1. Price Analysis
  • Current Price Trends (Per kg & Per Ton)
  • Price Fluctuation Factors (Raw Material Costs, Production, Trade Tariffs)
  • Regional Price Comparison (North America, Europe, Asia-Pacific, and Other)
  1. Production & Supply Volume
  • Global Production Capacity & Key Manufacturers
  • Production Process & Technological Developments
  • Raw Material Analysis
  1. Trade Analysis (Import & Export)
  • Major Exporting & Importing Countries
  • Trade Volume & Value Statistics
  • Impact of Trade Regulations & Policies
  1. Regional Analysis
  • North America (US and Canada)
  • Europe (UK, Germany, France, Italy, Spain, and Rest of Europe)
  • Asia-Pacific (China, Japan, South Korea, Taiwan, India, and Rest of Asia-Pacific)
  • Rest of the World (Latin America and Middle East and Africa)
  1. Competitive Landscape
  • Top Global Manufacturers & Market Share
  • Company Profiles & Key Developments
  • Mergers, Acquisitions & Investments
  1. Regulatory & Compliance Factors
  • FDA, REACH, and Other Regulatory Frameworks
  • Environmental & Safety Considerations
  • Emerging Policies Impacting Market Growth
  1. Conclusion & Strategic Recommendations
  • Key Takeaways for Stakeholders
  • Market Entry Strategies

 

What is Givosiran?
Givosiran is an RNA interference (RNAi) therapeutic used to treat patients with Acute Hepatic Porphyria (AHP). It targets and silences the enzyme involved in the pathway of porphyrin production, thereby reducing toxic intermediates and alleviating symptoms associated with AHP.
What is the market size for Givosiran?
The Givosiran API market is projected to grow steadily between 2025 and 2035, at a CAGR of 6.1%. This growth is driven by the increasing incidence of AHP and expanding applications of Givosiran in rare disease management.
What are the drivers for the Givosiran market?
Key drivers include the rising prevalence of Acute Hepatic Porphyria, increasing demand for personalized medicine, greater awareness of rare diseases, and ongoing research into new therapeutic applications for Givosiran.
Who are the key players operating in the Givosiran market?
Major players in the Givosiran API market include Alnylam Pharmaceuticals, Bayer AG, Sanofi S.A., Ionis Pharmaceuticals, Novartis, and Pfizer Inc.
Which region would exhibit the fastest growth in the Givosiran Market?
The Asia-Pacific region is expected to exhibit the fastest growth during the forecast period, driven by rising healthcare expenditures, expanding pharmaceutical manufacturing capabilities, and increasing awareness of cardiovascular disease treatments in countries like India and China.
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